PROGRAM

Saturday, July 30th

12:00 PM – 4:00 PM

Registration desk open

Pre-function outside of Elm Ballroom, SMC Campus Center

1:00 PM – 3:00 PM

Pre-Meeting Workshop 1: MSiReader Pro: An Intuitive and Innovative Vendor Neutral Software for Mass Spectrometry Imaging (Elm Ballroom, SMC Campus Center)

3:00 PM – 4:00 PM

Pre-Meeting Workshop 2: Strategic Design of MALDI Imaging Sample Preparation (Elm Ballroom, SMC Campus Center)

4:00 PM – 5:00 PM

Catacombs Tours (4:15 PM & 4:35 PM)

Westminster Hall

5:15 PM – 5:30 PM

Welcome Comments

Westminster Hall

5:30 PM – 6:30 PM

Opening Plenary, Advances in mass spectrometry imaging enable in-depth neuropharmacodynamics

Dr. Per Andrén

Westminster Hall

6:30 PM – 8:30 PM

Opening Reception- Cocktails and Bites

Westminster Hall

Sunday, July 31st

7:30 AM – 8:00 AM

Coffee & Pastry

8:00 AM – 9:30 AM    Microbial Interactions & Microenvironments

8:00 AM – 8:30 AM

Keynote: Watch this: specialized metabolite production in microbes

Speaker: Laura Sanchez

8:30 AM – 8:45 AM

Revealing the molecular universe of environmental microbiomes using spatially resolved mass spectrometry and multimodal imaging

Speaker: Chris Anderton    Abstract #: 10

8:45 AM – 9:00 AM

LPS-to-Lipid A-MSI (LLA-MSI) Coupled with Pre-washing for Enhanced Sensitivity

Speaker: Yang Hyojik    Abstract #: 31

9:00 AM – 9:15 AM

Lipid dysregulation as a pathogenic mechanism in Candida albicans pulmonary infection in wildtype and Cystic Fibrosis mouse models

Speaker: Alison Scott    Abstract #: 49

9:15 AM – 9:30 AM

MALDI Imaging of COVID-19 Lipid Storm in Human Lung and Bronchoalveolar Lavage Samples

Speaker: Caitlin Tressler    Abstract #: 2

9:30 AM – 10:00 AM

Coffee

10:00 AM – 11:45 AM    Informatics, Data Analysis, & Data Integration

10:00 AM – 10:15 AM

Sponsor Talk: Bruker 

Speaker: Kate Stumpo

10:15 AM – 10:45 AM

Keynote: AI for MSI with Cardinal and R

Speaker: Kylie Bemis

10:45 AM – 11:00 AM

Interpretable feature extraction from mass spectrometry imaging data via non-negative matrix factorization

Speaker: Kasun Pathirage   Abstract #: 30

11:00 AM – 11:15 AM

Integrated spatial metabolomics and machine learning reveal glycogen as an actionable target for pulmonary fibrosis

Speaker: Ramon Sun    Abstract #: 8

11:15 AM – 11:30 AM

Multimodal data integration and analysis technologies for constructing multi-scale molecular tissue atlases

Speaker: Heath Patterson    Abstract #: 28

11:30 AM – 1:00 PM

Lunch & Agilent Luncheon Seminar

Seminar: Targeted spatial quantitative imaging of metabolites in paraffin embedded bio-specimens using AP-MALDI coupled to triple quadrupole mass spectrometry and overview of AP-MALDI for imaging

Speakers: Xi Qiu & Venkateswarlu (Venkat) Panchagnula, PhD

1:00 PM – 2:30 PM    Emerging Techniques & New Instrumentation

1:00 PM – 1:30 PM

Keynote: New Directions in IR-MALDESI Mass Spectrometry Imaging

Speaker: David Muddiman

1:30 PM – 1:45 PM

Revealing the secret life of a human metabolon by metabolomics and high resolution mass spectrometry imaging

Speaker: Vidhi Pareek    Abstract #: 41

1:45 PM – 2:00 PM

Multimodal ultrahigh mass resolution mass spectrometry imaging using absorption mode 21T FTICR MS

Speaker: Gregory Vandergrift    Abstract #: 11

2:00 PM – 2:15 PM

High Performance Mass Spectrometry for Advanced Multimodal Molecular Imaging

Speaker:  Jeff Spraggins   Abstract #: 45

2:15 PM – 2:30 PM

Sponsor Talk: Waters

Speaker: Bindesh Shrestha

2:30 PM – 3:00 PM

Coffee

3:00 PM – 5:00 PM    Workshops 1 & 2

3:00 PM – 5:00 PM

Workshop 1: Multimodal IMS: Concepts and Practicalities of Integrating IMS, Microscopy and Other Data

3:00 PM – 5:00 PM

Workshop 2: Integration of metabolomics with transcriptomic and proteomic datasets: The whole is greater than the sum of its parts

5:00 PM – 6:30 PM

Cocktail Reception & Poster Session (A)

Monday, August 1st

7:30 AM – 8:00 AM

Coffee & Pastry

8:00 AM – 9:30 AM    Pharmacology & Toxicology

8:00 AM – 8:30 AM

Keynote: Mass spectrometry imaging in drug development: A brief history and its application for infectious diseases

Speaker: Claire Carter

8:30 AM – 8:45 AM

Gemcitabine Treatment Induced Lipidomic Changes in Pancreatic Tumor Xenograft Models in Mice

Speaker: Cameron Shedlock    Abstract #: 29

8:45 AM – 9:00 AM

Application of Highly Multiplexed Mass Spectrometry Imaging in Medicine Development

Speaker: Fang Xie    Abstract #: 6

9:00 AM – 9:15 AM

Revealing Sex and Alzheimer's Disease-related Changes in Spatial Localization of Brain Lipids in Mice using Mass Spectrometry Imaging

Speaker: Herana Kamal Seneviratne    Abstract #: 48

9:15 AM – 9:30 AM

Intended and Unintended Impacts of Internal Standard Normalization in Quantitative Imaging Mass Spectrometry

Speaker: Jeremy Barry    Abstract #: 15

9:45 AM – 10:00 AM

Coffee

10:00 AM – 11:45 AM    Cancer

10:00 AM – 10:30 AM

Keynote: Mass Spectrometry Imaging – Applications in Pathology

Speaker: Kristina Schwamborn

10:30 AM – 10:45 AM

From Tissue to Serum- Spatial Omics used to develop a novel biomarker for Cholangiocarcinoma

Speaker: Shaaron Ochoa-Rios    Abstract #: 23

10:45 AM – 11:00 AM

Using multimodal mass spectrometry imaging to iron out the mechanisms of ferroptosis in epithelial ovarian cancer

Speaker: Mike Taylor    Abstract #: 5

11:00 AM – 11:15 AM

Case Study of a Canine Sarcoma Within a Lipoma: Opportunities for Imaging MS in Veterinary Medicine

Speaker: Colleen Crouch    Abstract #: 12

11:15 AM – 11:30 AM

Investigation of Glutamine Utilization in Prostate Cancer Xenograft Tumors Using MALDI Imaging

Speaker: Natalie Dillman    Abstract #: 25

11:45 AM – 1:00 PM

Lunch & Discussion Reporting Standards

1:00 PM – 5:00 PM    Afternoon Activity: Aquarium & Free Time

5:00 PM – 6:30 PM

Cocktail Reception & Poster Session (B)

Tuesday, August 2nd

7:30 AM – 8:00 AM

Coffee & Pastry

8:00 AM – 9:30 AM    Tissue Mapping & Biomolecular Atlases

8:00 AM – 8:30 AM

Keynote: Mapping Spatial Distribution of Signaling Molecules in the Nervous System by MALDI Mass Spectrometry Imaging and Hyphenated Techniques

Speaker: Lingjun Li

8:30 AM – 8:45 AM

Spatial MALDI Mass Spectrometry Imaging of Hippocampal Chondroitin Sulfate Isomers Demonstrates Intraregional Differences Across Species

Speaker: Kimberly Alonge   Abstract #: 7

8:45 AM – 9:00 AM

Understanding patient outcome through MALDI glycan imaging of genetically characterized hepatocellular carcinoma tissue and serum.

Speaker: Andrew Delacourt    Abstract #: 39

9:00 AM – 9:15 AM

Identification and Spatial Distribution of Extracellular Matrix Proteins in Penile Tissue Scaffolds using MALDI Mass Spectrometry Imaging

Speaker: Sofia Nakuchima     Abstract #: 19

9:15 AM – 9:30 AM

Building Robust Spatial Metabolomics Methods for Creating Human Biomolecular Atlases

Speaker: Jessica Lukowski    Abstract #: 20

9:45 AM – 10:00 AM

Coffee

10:00 AM – 11:30 AM    New Applications

10:00 AM – 10:30 AM

Keynote: New Sample Preparation Strategies for Greater Biomolecule Coverage in MALDI Imaging Experiments

Speaker: Erin Seeley

10:30 AM – 10:45 AM

N-Glycomics Based Investigation of Pulmonary Immune Response in Post-Acute COVID-19 Patients

Speaker: Nicole Jenkinson    Abstract #: 4

10:45 AM – 11:00 AM

On-Tissue Derivatization of Volatile Metabolites for Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Speaker: Trevor Forsman    Abstract #: 38

11:00 AM – 11:15 AM

Machine Learning Analysis of Imaging MS Data of Human Retina Deposits Reveals Potential Mechanisms of Formation

Speaker: Kevin Schey    Abstract #: 21

11:15 AM – 11:30 AM

Detection of Increased Fucosylation Signatures in Advanced Metastatic Prostate Cancer Tissues using N-glycan MALDI Imaging Mass Spectrometry

Speaker: Richard Drake    Abstract #: 37

11:30 AM – 1:00 PM

Lunch & Presentation of Awards

1:00 PM – 3:00 PM    Workshops 3 & 4

1:00 PM – 3:00 PM

Workshop 3: An Introduction to SIMS, DESI, and LASEI for Mass Spectrometry Imaging (Part A) & DESI and Ambient Ionization (Part B)

1:00 PM – 3:00 PM

Workshop 4: Government Funding Workshop

END OF FORMAL SESSION